Gestanin (Allylestrenol)

Gestanin stimulates the secretory phase in the myometrium, creates conditions for the development of a fertilized egg, and contributes to the preservation of pregnancy.

Gestanin has a tocolytic effect, and it reduces the sensitivity of myometrium to oxytocin. It stimulates the development of the acini of the mammary glands, the secretory activity of trophoblasts, the production of aldosterone by the adrenal glands.

Gestanin increases the excretion of placental steroid metabolites and the secretion of endogenous progestogen increases fat stores and glucose utilization, promotes the accumulation of glycogen by the liver, normalizes the function of the placenta.

The dosage of Gestanin and how to use:

You need to swallow it with. The dosage is 5 mg of Gestanin 3 times a day (but not more than 20 mg) for 5-7 days before the termination of the symptoms.

With the usual miscarriage – 5 mg 2 times a day for at least 1 month after the critical period, then the dose can be reduced. The dose and duration of treatment with Gestanin are determined individually in each specific case.

Side effects of Gestanin:

On the part of the digestive system: dyspepsia, nausea, cholestatic jaundice.

Nervous system disorders: a headache, depression, insomnia or drowsiness.

On the part of the urinary system: fluid retention, edematous syndrome.

Others: thrombophlebitis, thromboembolism, weight gain, galactorrhea, swelling of the mammary glands, hyperthermia, decreased glucose tolerance.

Special instructions:

Patients with diabetes require regular monitoring of blood glucose levels when they use Gestanin.